"The epidemiology of rhabdomyosarcoma: attempting to identify the different susceptibility factors"

The Focus On Rhabdo Webinar Series continues on August 17th at 2PM Eastern with Dr. Philip Lupo.

Philip Lupo BCMWhile several investigators are interested in characterizing the genetic makeup of rhabdomyosarcoma tumors and in improving treatment outcomes among children diagnosed with rhabdomyosarcoma, less work has been done in terms of understanding susceptibility to this important malignancy. The goal of epidemiology is not to simply describe the distribution of diseases, but also to identify susceptibility factors for disease, which will ultimately aid in prevention efforts. The purpose of this webinar is to briefly review epidemiologic methods for evaluating susceptibility factors, outline what is currently known in terms of the epidemiology of rhabdomyosarcoma, and discuss future directions in epidemiologic studies of rhabdomyosarcoma.

IMPORTANT: This will be a moderated webinar. To protect our speakers from even a hint of 'practicing medicine over the internet' we ask that you send in your questions prior to the program. We will sort and compile them and try to ensure that all questions are answered - either within the talk or posed to the speaker by the moderator in the Q&A portion towards the end of the program. If you think of a question during the program, please use ClickMeeting's chat facility to ask the question and the moderator will, time permitting, ask the question to the speaker. Please use the comment form below to send your questions.

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Dr. Philip Lupo is a molecular epidemiologist and an Assistant Professor in the Section of Hematology-Oncology of the Department of Pediatrics at Baylor College of Medicine. He is also a member of the epiCenter of the Texas Children’s Cancer Center. He is currently collaborating with other researchers and clinicians in the Children’s Oncology Group (COG) to build a research program in the epidemiology of rhabdomyosarcoma. Dr. Lupo is also an active collaborator with the Centers for Disease Control and Prevention-funded National Birth Defects Prevention Study (NBDPS) and is part of a multidisciplinary team of experts assessing the intersection of childhood cancer and birth defects. The ultimate goal of Dr. Lupo’s research is to discover factors that can be used in childhood cancer prevention efforts and targeted interventions to limit the adverse consequences of childhood cancer treatment.

Recent Publications:

Maternal and birth characteristics and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
Lupo PJ, Danysh HE, Skapek SX, Hawkins DS, Spector LG, Zhou R, Okcu MF, Papworth K, Erhardt EB, Grufferman S., Cancer Causes Control. 2014 May 16. [Epub ahead of print] PMID: 24831857

Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman S., Int J Cancer. 2014 Jan 15;134(2):431-6. doi: 10.1002/ijc.28363. Epub 2013 Aug 1. PMID: 23824786

Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects.
Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H; National Birth Defects Prevention Study., Mol Genet Metab. 2014 Jan;111(1):46-51. doi: 10.1016/j.ymgme.2013.11.004. Epub 2013 Nov 18. PMID: 24332798