Recognizing subtle signs and symptoms of pediatric cancer

This is a link to a pre-publication copy of an article from Nursing2015 magazine I think we should all read and pass along to our friends and pediatricians. Recognizing subtle signs and symptoms of pediatric cancer By Paula Barbel, PhD, RN, PNP, and Kathleen Peterson, PhD, RN, PNP-BC CANCER IS A RARE occurrence in children…
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Nearly half of sarcoma surgeries done by nonsurgical oncology specialists

I found this while researching a current project. It dates back to July 8, 2013 but is significant in its findings, especially for the rhabdo community. The full post can be found on the UCDavis website - click here. Orthopedic oncologists and surgical oncologists, who have been trained in the complex procedures required to remove…
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An Invitation from the Cancer Knowledge Network

Cancer Knowledge Network (CKN) is owned by Multimed Inc., an international medical publishing and project development company, and publishers of Canada’s leading oncology journal, Current Oncology. CKN was created in 2011 to address the gap between scientific research and day to day living with cancer. It quickly grew and now directly addresses many areas of…
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Phase I trial of seneca valley virus (NTX-010) in children with relapsed/refractory solid tumors: A report of the children’s oncology group.

Burke MJ, Ahern C, Weigel BJ, Poirier JT, Rudin CM, Chen Y, Cripe TP, Bernhardt MB, Blaney SM. Journal Pediatr Blood Cancer. 2014 Oct 12. doi: Abstract BACKGROUND: To determine the MTD of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors. Patients (≥3-≤21 years) with neuroblastoma, rhabdomyosarcoma, or rare tumors with neuroendocrine features were…
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Prognostic model for predicting overall survival in children and adolescents with rhabdomyosarcoma

From Mimi Olsson The purpose of this study was to develop a prognostic model for the survival of pediatric patients with rhabdomyosarcoma (RMS) using parameters that are measured during routine clinical management. Conclusions This study provided an objective analysis of all currently available data for pediatric RMS from the SEER cancer registry. A nomogram based…
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Complete remission of a high risk metastatic rhabdomyosarcoma in an adolescent treated with a liposomal (Myocet®) regimen

From: Archive of Clinical Cases 2014; 1(2):52-55 () Abstract We report the case of a very high risk metastatic rhabdomyosarcoma teenager treated with induction therapy using only liposomal doxorubicin (Myocet®) because of his extremely bad condition. A near complete remission was obtained after 2 courses. Then he received conventional chemotherapy according to the EpSSG protocol,…
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Declining Childhood and Adolescent Cancer Mortality

Declining Childhood and Adolescent Cancer Mortality Malcolm A. Smith, MD, PhD; Sean F. Altekruse, DVM, PhD; Peter C. Adamson, MD; Gregory H. Reaman, MD; and Nita L. Seibel, MD To go to the web link at Wiley Online Library, Click Here Treatment of childhood cancer is 1 of the important success stories of 20th century…
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YAPping About Differentiation Therapy in Muscle Cancer

YAPping About Differentiation Therapy in Muscle Cancer MN Svalina, C Keller - Cancer Cell, 2014 This article is linked to "The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation" (Tremblay, ) which was the basis for Samantha Olson's article "Cause of Rare Childhood Cancer, Rhabdomyosarcoma, Discovered: May…
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Treating Cancer With Bacteria Shows Real Promise

In a groundbreaking study, researchers say injecting bacteria into a tumor helped shrink it Alice Park - August 13, 2014 Time Online Bacteria are generally considered more foe than friend, but that may change, if results from a pioneering study are confirmed. Reporting in the journal Science Translational Medicine, scientists led by Dr. Saurabh Saha,…
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Gene Mutation Linked to Aggressive Form of Sarcoma Affecting Children and Young Adults

From OnCancer - Memorial Sloan Kettering Cancer Center By Eva Kiesler, PhD, Science Writer/Editor | Wednesday, August 6, 2014 Researchers at Memorial Sloan Kettering have discovered a gene mutation that may explain why a subset of patients with rhabdomyosarcoma — a rare cancer that affects mainly children and young adults — have a particularly aggressive…
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