Metastatic rhabdomyosarcoma initially diagnosed on the bone marrow

Metastatic rhabdomyosarcoma initially diagnosed on the bone marrow Andrés E. Quesada and Rashmi Kanagal-Shamanna | Blood 2016 128:2189; | See Original Here A 15-year-old boy presented with a rapid-onset right-sided facial mass, thrombocytopenia (114 × 109/L), and elevated serum lactate dehydrogenase. A computed tomography scan demonstrated a maxillary sinus and nasopharyngeal mass with extensive cervical lymphadenopathy. Bone…
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Novel microRNA Regulatory Network Has Important Therapeutic Implications in Rhabdomyosarcoma

Novel microRNA Regulatory Network Has Important Therapeutic Implications in Rhabdomyosarcoma Interview with: Riccardo Taulli, PhD Assistant Professor of Biochemistry Dept. of Oncology, University of Turin Via Santena 5, 10126 Torino, Italy : What is the background for this study? Response: Rhabdomyosarcoma is a muscle-derived pediatric cancer for which therapeutic options have not improved significantly over…
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Researchers develop algorithm to find precise cancer treatments

Researchers develop algorithm to find precise cancer treatments August 10, 2016 | eCancerNews | See Original Here University of Hawai'i Cancer Center researchers developed a computational algorithm to analyse "Big Data" obtained from tumour samples to better understand and treat cancer. "A growing problem in cancer research is figuring out how to analyse the many…
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Selinexor Shows Promise in Phase I Sarcoma Trial

Selinexor Shows Promise in Phase I Sarcoma Trial Dave Levitan | July 26, 2016 | CancerNetwork | See Original Here A phase I trial of selinexor, an inhibitor of the nuclear export compound exportin 1 (XPO1), found the drug was reasonably well tolerated and showed some activity in patients with advanced soft-tissue or bone sarcoma…
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Fusion-Negative Sarcoma Survivors Have Increased Risk of Second Malignancies

Fusion-Negative Sarcoma Survivors Have Increased Risk of Second Malignancies Dave Levitan | August 4, 2016 | CancerNetwork | See Original Here Survivors of fusion-negative (F−) sarcomas have a higher risk of developing a second malignant neoplasm than those who had fusion-positive (F+) sarcomas, according to a new study, which could offer guidance on surveillance of these…
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Tracking Cancer In Real Time

Tracking Cancer In Real Time By Anna Gorman | July 21, 2016 | Kaiser Health News | See Original Here California is overhauling the way it collects information for its massive cancer database in the hope of improving how patients are treated for the disease. Pathologists at a dozen hospitals in the state are part of a pilot…
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Clinical studies of PBS protons

Clinical studies of PBS protons Cynthia E Keen | MedicalPhysicsWeb | July 19, 2016 | See Original Here Switzerland's Paul Scherrer Institute (PSI) developed the technique of pencil-beam scanning (PBS) proton therapy 20 years ago and continues to be a pioneering global leader in its use. In newly published studies, researchers at PSI's Center for…
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‘Liquid biopsy’ may show whether cancer drugs are working

'Liquid biopsy' may show whether cancer drugs are working Amy Norton | HealthDay News | July 13, 2016 | From UPI News | See Original Here Researchers have developed a blood test that might allow doctors to know quickly whether a cancer drug is working. The technique is in the early stages of testing, and not…
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Cancer cell lines predict drug response and accelerate personalized medicine

Cancer cell lines predict drug response and accelerate personalized medicine July 7, 2016 | ScienceDaily | See Original Here Source: Wellcome Trust Sanger Institute Summary: Research has shown that patient-derived cancer cell lines harbor most of the same genetic changes found in patients' tumors, and could be used to learn how tumors are likely to respond to new…
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