From Google Scholar Alerts
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Comparative Pathology of Canine Soft Tissue Sarcomas: Possible Models of Human Non-rhabdomyosarcoma Soft Tissue Sarcomas
M Milovancev, M Hauck, C Keller, LW Stranahan… - Journal of Comparative …, 2014
Summary Comparative analyses of canine and human soft tissue sarcomas (STSs) are lacking. This study compared the histological and immunohistochemical (labelling for desmin, smooth muscle actin [SMA], CD31, pancytokeratin, S100 and CD34) appearance ...

A Case of Rhabdomyosarcoma in Parapharyngeal Space
E Park, K Lee, MW Park, KY Jung - Korean Journal of Otorhinolaryngology-Head and …, 2014
Abstract Rhabdomyosarcoma is a highly aggressive malignant tumor that originates from mesenchymal cell and invades soft tissue. While the head and neck is the common site of the rhabdomyosarcoma, the parapharyngeal space is rarely reported as a primary site of ...

Potential role of hypoxia imaging using 18F-FAZA PET to guide hypoxia-driven interventions (carbogen breathing or dose escalation) in radiation therapy
A Bol, D Labar, O Karroum, V Bol, B Jordan, V Grégoire… - Radiotherapy and Oncology, 2014
... Material and methods. Two hypoxic rat tumor models were used: rhabdomyosarcoma and 9L-glioma. ... Rats bearing Rhabdomyosarcoma were divided into three groups: non-irradiated (control); irradiated with 15 Gy and irradiated with 20 Gy. ...

Phase II study of cixutumumab in combination with temsirolimus in pediatric patients and young adults with recurrent or refractory sarcoma: A report from the children's oncology group
LM Wagner, M Fouladi, A Ahmed, MD Krailo, B Weigel… - Pediatric Blood & Cancer, 2014
... We evaluated the activity of the anti-IGF-1R antibody cixutumumab with the mTOR inhibitor temsirolimus in patients with relapsed or refractory Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, and other soft tissue sarcoma, using the recommended dosages from a ...

Urothelial bladder tumour in childhood: A report of two cases and a review
UN Rifat, NY Hamadalla, KCC Safi, SS Al Habash… - Arab Journal of Urology, 2014
... Alanee and Shukla [49] identified 140 cases of bladder cancer, with PUNLMP and rhabdomyosarcoma comprising 50.7% and 36.4% of the tumours, respectively. ... Fifty-one cases of embryonal rhabdomyosarcoma were identified. ...

Sclerosing Rhabdomyosarcoma
SJ Maygarden
Virtual Slides as well as Still Images are displayed below. For the fastest viewing of virtual slides, click: under each thumbnail image below. You must have Aperio ImageScope installed on your PC. ... If you do not already have Aperio ImageScope, Windows users with ...

In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells
J Niesen, H Brehm, C Stein, N Berges, A Pardo… - Journal of Cancer Research …, 2014
Purpose Rhabdomyosarcoma (RMS) is a rare and aggressive soft tissue sarcoma with limited treatment options and a high failure rate during standard therapy. New therapeutic strategies based on targeted immunotherapy are therefore much in demand. The ...

Primary Cutaneous Rhabdomyosarcoma
JM Gardner, BR Smoller - Rare Malignant Skin Tumors, 2015
Abstract Rhabdomyosarcoma is a malignant mesenchymal neoplasm with skeletal muscle differentiation that typically occurs in the deep soft tissue or viscera. Three subtypes comprise the majority of cases of rhabdomyosarcoma: embryonal, alveolar, and ...

Does aggressive local treatment have an impact on survival in children with metastatic rhabdomyosarcoma?
MB Arush, V Minard-Colin, V Mosseri, AS Defachelles… - European Journal of Cancer, 2014
Purpose Due to the extensive initial distant tumour spread in metastatic rhabdomyosarcoma, the importance of local treatment is sometimes underestimated. A retrospective study was conducted to identify the prognostic value of aggressive local treatment in paediatric ...

Pelvic alveolar rhabdomyosarcoma in a young adult
D Reisner, C Amadi, S Patel, R Surampudi, I Beckman - Radiology Case Reports, 2014
Abstract Rhabdomyosarcomas are rare soft tissue tumors in adults. Accounting for nearly 5% of childhood cancers, they represent less than 0.03% of adult malignancies. Three different subtypes of rhabdomyosarcoma have been described; embryonal, alveolar and ...

Li-Fraumeni syndrome: A case report
MP Ilić, K Aleksandar, B Markov, I Mijatov, S Mijatov… - Vojnosanitetski pregled, 2014
... 7, the American physi- cians who first recognized and described the syndrome. In the study on 648 childhood rhabdomyosarcoma patients, they identified 4 families in which siblings or cousins had a child- hood sarcoma. These ...

Common Pediatric Head and Neck Congenital/Developmental Anomalies
JK LaPlante, NS Pierson, GL Hedlund - Radiologic Clinics of North America, 2015
... If CECT and or MR imaging are performed as the initial imaging studies in the clinical context of fibromatosis colli, they may suggest that the SCM mass is indeterminate or, worse, suggest the possibility of soft tissue sarcoma (rhabdomyosarcoma) (Table 5). Such an ...

Deep Sequencing the microRNA profile in rhabdomyosarcoma reveals down-regulation of miR-378 family members
F Megiorni, S Cialfi, HP McDowell, A Felsani… - BMC Cancer, 2014
Background Rhabdomyosarcoma (RMS) is a highly malignant tumour accounting for nearly half of soft tissue sarcomas in children. MicroRNAs (miRNAs) represent a class of short, non-coding, regulatory RNAs which play a critical role in different cellular processes. Altered ...

Bifocal Adult Embryonal Rhabdomyosarcoma
SHA Naqvi, MY Bandukda, SHS Naqvi
ABSTRACT Embryonal rhabdomyosarcoma is commonly seen in young children, its occurrence in the adult population is rare. Here, we describe a 36-year-old male with the diagnosis of adult embryonal rhabdomyosarcoma who was admitted with two large ...

Rhabdomyosarcoma of Orbit: A Rare Case Report and Review
R Nagarkar, S Roy, M Akheel, V Palwe, N Kulkarni - IJSS, 2014
Rhabdomyosarcoma (RMS) is a highly fulminant, mesenchymal malignant tumor and is considered to be one among life-threatening disease in the present decades. It is considered to be most common malignant neoplasm of the head and neck region with 10 ...

PLK1 phosphorylates PAX3-FOXO1 the inhibition of which triggers regression of alveolar rhabdomyosarcoma
V Thalhammer, LA Lopez-Garcia, DH Martin, R Hecker… - Cancer Research, 2014
Abstract Pediatric tumors harbor very low numbers of somatic mutations and therefore offer few targets to improve therapeutic management with targeted drugs. In particular, outcomes remain dismal for patients with metastatic alveolar rhabdomyosarcoma (aRMS), where the ...

Abstract A14: Canonical WNT/β-catenin pathway activation suppresses embryonal rhabdomyosarcoma growth and self-renewa
E Chen, M DeRan, KB Grandinetti, M Ignatius, R Clagg… - Molecular Cancer Research, 2014
Embryonal rhabdomyosarcoma (ERMS) is a common pediatric malignancy of muscle with relapse being the major clinical challenge. Self-renewing tumor-propagating cells (TPCs) drive cancer relapse and are confined to a molecularly definable subset of ERMS cells. To identify ...

Successful treatment of metastatic rhabdomyosarcoma with radiochemotherapy and allogeneic hematopoietic stem cell transplantation
F Yamazaki, T Osumi, N Shigematsu, H Morioka… - Japanese Journal of Clinical …, 2014
Abstract We report a case of a 21-year-old man with alveolar rhabdomyosarcoma primarily in the right hand with lymph node, lung, bone and bone marrow metastases. Complete remission was achieved after intensive chemotherapy and radiotherapy of the primary and ...

Preliminary Results of a Phase II Trial of Proton Radiotherapy for Pediatric Rhabdomyosarcoma
MM Ladra, JD Szymonifka, A Mahajan, AM Friedmann… - Journal of Clinical Oncology, 2014
Purpose This prospective phase II study was designed to assess disease control and to describe acute and late adverse effects of treatment with proton radiotherapy in children with rhabdomyosarcoma (RMS). Patients and Methods Fifty-seven patients with localized RMS ...