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Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma
W Fu, P Asp, B Canter, BD Dynlacht - Proceedings of the National Academy of …, 2014
Abstract The primary cilium acts as a cellular antenna, transducing diverse signaling pathways, and recent evidence suggests that primary cilia are important in development and cancer. However, a role for cilia in normal muscle development and rhabdomyosarcoma ( ...

Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma
K Miyoshi, K Kohashi, F Fushimi, H Yamamoto… - Human Pathology, 2014
Abstract CXCR4 expression is reportedly correlated with both VEGF expression and poor prognosis in a variety of cancers. Its relation to CXCR7 is also noted in several malignancies, including rhabdomyosarcoma (RMS) cell lines. However, the correlations ..

A Rare Case of Testicular Embryonal Rhabdomyosarcoma Detected Incidentally on Bone Scan
GM Currie, C Skilton - Journal of Medical Imaging and Radiation Sciences, 2014
Abstract The role of nuclear medicine diagnostic bone scanning is well established, and the potential for detecting incidental findings is well-known. This case provides an insight into the specific role bone scanning plays in unraveling a complex clinical case. Furthermore, ...

Rhabdomyosarcoma Arising in a Giant Congenital Melanocytic Nevus
MP Christman, JK Kerner, C Cheng, A Piris, AG Nepo… - Pediatric Dermatology, 2014
Abstract A number of lesions have been documented to arise within congenital melanocytic nevi (CMNs). Although the most frequent malignancy arising within a CMN is melanoma, the association between rhabdomyosarcoma and CMN has rarely been documented. We ...

Cranial metastatic alveolar rhabdomyosarcoma mimicking hematological malignancy in an adolescent boy
T Patiroglu, B Isik, E Unal, O Canoz, K Deniz… - Child's Nervous System, 2014
Background Widespread alveolar rhabdomyosarcoma (ARMS) with bone marrow involvement and with an unknown primary tumor, especially presenting with acute tumor lysis syndrome can be easily misdiagnosed as a hematological malignancy. Furthermore, ...

Secondary malignant transformation of testicular teratomas: Case series and literature review.
L García-Labastida, GS Gómez-Macías… - Actas urologicas espanolas, 2014
... The predominante malignant somatic component were sarcomas; two cases of
chondrosarcoma, one rhabdomyosarcoma, and one case showing foci of chondrosarcoma
and rhabdomyosarcoma. The case of osteosarcoma is notable for its rarity. ...

Parenteral nutrition in patients with inborn errors of metabolism – a therapeutic problem
L Kaluzny, M Szczepanik, Z Siwinska-Mrozek… - Eur Rev Med Pharmacol Sci, 2014
... Thus, limitations of intravenous lipid intake made it diffi- cult to maintain a good nutritional status.The third case was phenylketonuria associated with a facial region tumour (rhabdomyosarcoma), in which para-enteral nutrition was complicated because of a high ...

Targeted polytherapy in small cell sarcoma and its association with doxorubicin
S Dumont, D Yang, AG Dumont, D Reynoso, JY Blay… - Molecular Oncology, 2014
... This work identifies a combination of targeted agents and doxorubicin that are effective against small cell sarcoma cell lines. Methods. Three small cell sarcoma cell lines were studied: RD18 (rhabdomyosarcoma), A204 (undifferentiated sarcoma) and TC 71 (Ewing's sarcoma). ...

Class I ADP-Ribosylation Factors Are Involved in Enterovirus 71 Replication
J Wang, J Du, Q Jin - PloS one, 2014
... GBF1 was also identified as a cellular factor crucial for EV71 replication in cells. Results. Expression of Class I Arfs is upregulated with EV71 infection. We previously showed that cellular COPI activity was required for EV71 replication in rhabdomyosarcoma (RD) cells [11]. ...