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Epithelioid rhabdomyosarcoma: a clinicopathologic and molecular study.
A Zin, R Bertorelle, P Dall'igna, C Manzitti, C Gambini… - The American journal of …, 2014
Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma and is mostly
represented by the embryonal (ERMS) and alveolar (ARMS) histotypes. Whereas ERMS
shows variable genetic alterations including TP53, RB1, and RAS mutations, ARMS ...

Prognostic Risk Factors for the Development of Scoliosis After Chest Wall Resection for Malignant Tumors in Children
A Scalabre, R Parot, F Hameury, V Cunin, JL Jouve… - The Journal of Bone & Joint …, 2014
Surgical resection of a malignant tumor of the chest wall in children may result in the development of progressive scoliosis. The aim of this study was to identify the risk factors associated with scoliosis following resection of a tumor of the chest wall and to evaluate the prevalence and characteristics of the scoliosis

MiR-1 targets PIK3CA and inhibits tumorigenic properties of A549 cells
QQ Yu, H Wu, X Huang, H Shen, YQ Shu, B Zhang… - Biomedicine & …, 2014
... MicroRNA-1 (miR-1) has been identified as a tumor suppressor in various human cancers, such
as lung cancer, head and neck squamous cell carcinoma, colorectal cancer, prostate cancer,
bladder cancer, thyroid carcinoma, rhabdomyosarcoma, and hepatocellular carcinoma ...

De Novo 13q13.3-21.31 deletion involving RB1
gene in a patient with hemangioendothelioma of
the liver

N Rapini, R Lidano, S Pietrosanti, G Vitiello, C Grimaldi… - Italian Journal of Pediatrics, 2014
... Chromosome 13 has one of the lowest gene densities, although several tumor suppressor genes
are present on the long arm and are involved in different types of tumors such as breast cancer
(BRCA2), alveolar rhabdomyosarcoma (FOXO1A) and retinoblastoma (RB1) [1]. The ...

Pericardial synovial sarcoma: challenges in diagnosis and management
P Phatak, J Khanagavi, WS Aronow, S Puri, Y Yusuf… - F1000Research, 2014
... series have shown the prevalence of primary cardiac tumors to be approximately 0.02% 6 . Soft
tissue sarcomas account for 37% of these primary cardiac tumors 7 . In descending order of
frequency, these are angiosarcoma, fibrosarcoma, rhabdomyosarcoma, and malignant ...

Receptor-interacting protein 1 increases chemoresistance by maintaining inhibitor of apoptosis protein levels and reducing reactive oxygen species through a microRNA-146a-mediated catalase pathway
Q Wang, W Chen, L Bai, W Chen, MT Padilla, AS Lin… - Journal of Biological …, 2014
... inducing cytotoxicity (30). Similarly, suppressing RIP1 attenuated apoptosis caused
by the combination of TRAIL receptor 2 antibody (lexatumumab) and IAP inhibitors
in rhabdomyosarcoma cells (31). These results suggest ...

Novel inhibitors of signal transducer and activator of transcription 3 signaling pathway: an update on the recent patent literature
A Lavecchia, C Di Giovanni, C Cerchia - Expert Opinion on Therapeutic Patents, 2014
... and cyclin D1. In addition, 1 induced cell growth inhibition and apoptosis through
the caspase pathway of human breast carcinoma and rhabdomyosarcoma cells
harboring constitutively active STAT3 [25,26]. Molecular docking ...

[PDF] Sarcoma Immunotherapy: Past Approaches and Future Directions
S D'Angelo, WD Tap, GK Schwartz, RD Carvajal
... larger tumors, is the mainstay of treatment.[2] Perioperative chemotherapy is used in specific
subtypes such as rhabdomyosarcoma, osteosarcoma and Ewing's sarcoma.[2] Dependent ...
fibrosarcoma, rhabdomyosarcoma, hemangiosarcoma and undifferentiated sarcoma which is ...