From Google Scholar Alerts
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Whole-lung irradiation in the treatment of metastatic synovial sarcoma
NK Gerber, PA Meyers, MP LaQuaglia, SL Wolden - Pediatric Blood & Cancer, 2014
... Whole-lung irradiation (WLI) is standard of care in the treatment of patients with rhabdomyosarcoma, Ewing sarcoma, and Wilms tumor and pulmonary metastases. ... Characteristics and outcomes of rhabdomyosarcoma patients with isolated lung metastases from IRS-IV. ...

The Impact of Psychosocial Needs of Adolescent and Young Adult Cancer Patients: An Analysis of Clinical Trial Participation and Adherence
K Jensen - 2014
... seen in the increased use of randomized clinical trials in childhood Rhabdomyosarcoma (RMS). 1 ... 1 Other sarcomas such as non- Rhabdomyosarcoma soft-tissue sarcomas (NRSTSs) have received little to no study through clinical trial and none stratified for age. ...

Uterıne sarcoma ın a 14 year-old gırl presentıng wıth uterıne rupture
J Özcan, Ö Dülger, L Küpelioğlu, Aİ Gönenç, A Erşahin - Gynecologic Oncology Case …, 2014
... preoperative diagnostic features and the intraoperative macroscopic apperance of the mass, resembled to those of our patient.The microscopic findings revealed spindle cells, hemorrhagic
necrosis but immunohystochemical staining revealed rhabdomyosarcoma, atypical for ...

EWS-WT1 oncoprotein activates neural reprogramming factor ASCL1 and promotes neural differentiation
HJ Kang, JH Park, WP Chen, S Im Kang, K Moroz… - Cancer Research, 2014
... genes that are up-regulated (>2-fold) in DSRCT compared to either Ewing sarcoma (ES), alveolar rhabdomyosarcoma (ARMS) or alveolar soft part sarcoma (ASPS) revealed an enrichment of neural ... Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. ...

MEK inhibitor effective against proliferation in breast cancer cell
Y Zhou, H Hu, W Meng, L Jiang, X Zhang, J Sha, Z Lu… - Tumor Biology, 2014
... miR-203 played a similar role in rhabdomyosarcoma, which was frequently down-regulated by promoter hypermethylation in both RMS cell lines and RMS biopsies and could be reactivated by DNA- demethylating agents [18]. ...

Advances in Patient-Derived Tumor Xenografts: From Target Identification to Predicting Clinical Response Rates in Oncology
E Rosfjord, J Lucas, HP Gerber - Biochemical Pharmacology, 2014
Most oncology compounds entering clinical development have passed stringent preclinical pharmacology evaluation criteria. However, only a small fraction of expe.

PARP inhibitor attenuated colony formation can be restored by MAP kinase inhibitors in different irradiated cancer cell lines
E Hocsak, A Cseh, A Szabo, S Bellyei, E Pozsgai… - International Journal of …, 2014
... and others 2011. MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals. Mol Cancer Ther 10: 159-68. McCubrey JA, Steelman ...

Amplification of the Insulin-like Growth Factor 1 Receptor Gene is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression
AAJ Tamaya Castro Ribeiro, MQ Almeida…
... Bridge JA, Liu J, Qualman SJ, Suijkerbuijk R, Wenger G, Zhang J, et al. Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes. ...

Septic shock: Rapid recognition and initial resuscitation in children
O reprint from UpToDate, SL Weiss, WJ Pomerantz…
Sepsis is a clinical syndrome complicating severe infection that is characterized by systemic inflammation, immune dysregulation, microcirculatory derangements, and end-organ dysfunction. There is a continuity of severity ranging from sepsis to sever.