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Lineage of origin in rhabdomyosarcoma informs pharmacological response
J Abraham, Y Nuñez-Álvarez, S Hettmer, E Carrió… - Genes & Development, 2014
Abstract Lineage or cell of origin of cancers is often unknown and thus is not a consideration in therapeutic approaches. Alveolar rhabdomyosarcoma (aRMS) is an aggressive childhood cancer for which the cell of origin remains debated. We used conditional genetic mouse ...

P0050 Survival of children with rhabdomyosarcoma: Experience of the National Cancer Institute Egypt
AA Ali, MF Fawzy, IF Fakhr - European Journal of Cancer, 2014
Background Survival rates of paediatric rhabdomyosarcoma have improved tremendously
during the past decade by the development of risk stratification. This approach has favoured tailoring of treatment using multi-therapeutic modalities. Methods Patients were given ...

An update on mesenchymal tumors of the head and neck
BC Dickson - Diagnostic Histopathology, 2014
... The differential diagnosis for low-grade sinonasal sarcoma with neural and myogenic
features includes malignant peripheral nerve sheath tumor, fibrosarcoma, synovial
sarcoma, and rhabdomyosarcoma. Admittedly, malignant ...

Fifteen-minute consultation: Investigation and management of childhood epistaxis
S Siddiq, J Grainger - Archives of disease in childhood-Education & practice …, 2014
... Inverted papilloma. Malignant. Rhabdomyosarcoma. Lymphoma. Vascular abnormalities.
Hereditary haemorrhagic telangiectasia. Haemangioma. ... The head and neck area is the
commonest site of rhabdomyosarcoma in children, and can also present with severe epistaxis. ...

Transurethral needle biopsy: a novel technique for pathologic diagnosis of bladder tumors in children
M Lightfoot, R Li, M Alsyouf, L Nicolay, D Chamberlin - Journal of Pediatric Urology, 2014
... Although not presented in this small case series, rhabdomyosarcoma is the most common
malignancy of the bladder in children. ... [3]; HY Wu, HM Snyder 3 rd , RB Womer; Genitourinary rhabdomyosarcoma: which treatment, how much, and when? J Pediatr Urol, 5 (2009), pp. ...

Bioactive Lipids, LPC and LPA, are Novel Pro-metastatic Factors and Their Tissue Levels Increase in Response to Radio/Chemotherapy
G Schneider, ZP Sellers, A Abdel-Latif, AJ Morris… - Molecular Cancer Research, 2014
... Running title: Bioactive lipids and rhabdomyosarcoma Key words: zysophosphatidylcholine (LPC), lysophosphatidic acid (LPA), rhabdomyosarcoma (RMS), metastasis Correspondence: Prof. ... inflammation, proliferation, and apoptosis. Rhabdomyosarcoma (RMS) is common in ...

Identification of Luteolin as Enterovirus 71 and Coxsackievirus A16 Inhibitors through Reporter Viruses and Cell Viability-Based Screening
L Xu, W Su, J Jin, J Chen, X Li, X Zhang, M Sun, S Sun… - Viruses, 2014
... 2.1. Cells and Drug Library 293T cells, RD cells (human embryonal rhabdomyosarcoma), and Vero cells were cultured as monolayers in Dulbecco‟s modified Eagle medium (DMEM) (Sigma) supplemented with 10% fetal calf serum (FCS) (10% FCS-DMEM). ...

Retardation of C2C12 myoblast cell proliferation by exposure to low-temperature atmospheric plasma
N Nakai, R Fujita, F Kawano, K Takahashi, T Ohira… - The Journal of Physiological …, 2014
... Abstract As the first step in evaluating the possibility of low-temperature atmospheric plasma for clinical applica- tions in the treatment of rhabdomyosarcoma (RMS), we determined the effects of plasma exposure on C2C12 myoblasts. ...

Orbital tumors in USA: Difference in survival patterns
WM Hassan, AS Alfaar, MS Bakry, S Ezzat - Cancer Epidemiology, 2014
... Further studies are needed to determine if the difference between embryonal
and alveolar rhabdomyosarcoma observed survival rates are statistically significant.
Rhabdomyosarcomas. 8900/3: Rhabdomyosarcoma, NOS, 7, 4, 3, 4, 2, 1. ...

Optimized cell transplantation using adult rag2 mutant zebrafish
Q Tang, NS Abdelfattah, JS Blackburn, JC Moore… - Nature Methods, 2014
... irradiation. We next wanted to assess the utility of our model to engraft a diversity
of transgenic zebrafish cancers including T-cell acute lymphoblastic leukemia
(T-ALL), embryonal rhabdomyosarcoma (ERMS) and melanoma. ...

Predictors of 7- and 30-day mortality in pediatric intensive care unit patients with cancer and hematologic malignancy infected with Gram-negative bacteria
P de Oliveira Costa, EH Atta, ARA da Silva - The Brazilian Journal of Infectious …, 2014
... The most frequently occurring underlying diseases in the patients with 7-day mortality
rhabdomyosarcoma (25%), acute lymphoblastic leukemia (12.5%), acute myeloid leukemia
(12.5%), osteosarcoma (12.5%), central nervous system tumor (12.5%), retinoblastoma (12.5 ...

Febrile neutropenia in pediatric cancer patients: Experience from a tertiary health care facility of Pakistan
MM Alam, Z Fadoo - Pediatric Infectious Disease, 2014
... patients as compare to ALL. 8 A diagnosis of lymphoma and osteosarcoma/Ewing's
sarcoma or rhabdomyosarcoma was associated with a significant reduction in risk
of composite adverse outcome. This is consistent with studies ...