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An adult spindle cell rhabdomyosarcoma in the head and neck region with long-term survival: a case report

S Hartmann, G Lessner, T Mentzel, AC Kübler… - Journal of Medical Case …, 2014
Conclusions In adults, the spindle cell rhabdomyosarcoma tumor is very rare in the head and neck region. In contrast to childhood tumors, spindle cell rhabdomyosarcoma in adulthood is often associated with a poor prognosis. In the present case, the radical ...

Age-related Toxicity in Patients With Rhabdomyosarcoma: A Report From the Children's Oncology Group
S Altaf, F Enders, E Lyden, SS Donaldson, D Rodeberg… - Orbit, 2014
Summary: On the Fourth Intergroup Rhabdomyosarcoma study, older children experienced excessive neurotoxicity, whereas younger children had increased myelosuppression. The purpose of this study was to determine whether the same pattern of toxicity was seen on ...

Tumoricidal Effect of Hematite (α-Fe2O3) and SiO2 Nanoparticles in Human Rhabdomyosarcoma Cell Line
M Hammad Aziz, M Fatima, M Waseem, M Afzal… - Advanced Materials …, 2014
Nanotechnology provides the opportunity for the development of new materials in the nanometer size range with many potential applications in biological sciences and clinical medicine. RD (muscle cancer cell line) was seeded out in 25 cm 2 plastic tissue culture ...

CXCR2 antibodies for antitumor immunity
L Martz - SciBX: Science-Business eXchange, 2014
... 1 By blocking CXC chemokine receptor 2, the team prevented migration of myeloid-derived suppressor cells and increased the efficacy of programmed cell death 1–targeting mAbs in a mouse model of rhabdomyosarcoma. ...

Phase I Clinical Trial of Ifosfamide, Oxaliplatin, and Etoposide (IOE) in Pediatric Patients With Refractory Solid Tumors.
CG Lam, WL Furman, C Wang, SL Spunt, J Wu, P Ivy… - Journal of Pediatric …, 2014
... other therapy. SD was seen in 9 patients (6 neuroblastoma, 2 rhabdomyosarcoma, 1 carcinoma) after 2 courses with a median duration of 16 weeks. All but TABLE 1. Characteristics of 17 Eligible Patients Characteristics N (%) Median ...

MicroRNAs and ceRNAs: therapeutic implications of RNA networks
DE Giza, C Vasilescu, GA Calin - Expert Opinion on Biological Therapy, 2014
... are cancer-associated networks was provided by Ala et al., who found that the network involving of the oncogenic PAX/FKHR translocation [commonly involving paired box (PAX3) or PAX7 and fork head box O1] was present in 90% of alveolar rhabdomyosarcoma, its ceRNAs ...

Immunotherapy: Two hits are better than one
GK Alderton - Nature Reviews Cancer, 2014
... microenvironment. Lara Crow/NPG. Highfill et al. used a syngeneic mouse model of embryonal rhabdomyosarcoma (ERMS), a type of paediatric sarcoma, in which M3-9-M mouse ERMS cells are inoculated into female mice. M3 ...

Skeletal Muscle Expression of the Adhesion-GPCR CD97: CD97 Deletion Induces an Abnormal Structure of the Sarcoplasmatic Reticulum but Does Not Impair Skeletal Muscle Function
T Zyryanova, R Schneider, V Adams, D Sittig, C Kerner… - PLOS ONE, 2014
... The human rhabdomyosarcoma cell line Hs729.T and the murine cell lines RAW 264.7 (monocyte/macrophage), C2C12 (myoblastic), 3H3/10T1/2 and 3T3 (fibroblastic), and CMT-93 (rectal carcinoma) were purchased from the American Type Culture Collection (ATCC ...