Recent Papers on Rhabdomyosarcoma – 13 Nov 2014
From Google Scholar Alerts
Please note that some are abstracts requiring subscriptions or purchase of the full article, others provide a more comprehensive view of the paper.
GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis
RK Srivastava, SZ Kaylani, N Edrees, C Li… - Oncotarget, 2014
Rhabdomyosarcoma (RMS) typically arises from skeletal muscle. Currently, RMS in patients with recurrent and metastatic disease have no successful treatment. The molecular pathogenesis of RMS varies based on cancer sub-types. Some embryonal RMS but not other sub-types ...
A novel trial of topotecan, ifosfamide, and carboplatin (TIC) in children with recurrent solid tumors
K Radhakrishnan, A Lee, LA Harrison, E Morris… - Pediatric Blood & Cancer, 2014
... Pre-clinical studies have demonstrated the efficacy of topotecan, a semi-synthetic camptothecin analog, on multiple tumor cell lines and xenograft models, including neuroblastoma, osteosarcoma, Ewing and Wilms tumor, and rhabdomyosarcoma . ...
Rhabdomyosarcoma in Adolescents. A Report From the AIEOP Soft Tissue Sarcoma Committee
MD Pastore, MD Giovanni Cecchetto… - 2 ANALISI DATI TOPOTECAN/ …
BACKGROUND: In many types of cancer, the survival rates are reported to be less favorable for adolescents compared with younger children. To investigate whether this is true for adolescents with rhabdomyosarcoma (RMS), the results obtained in patients enrolled in ... [NOTE: begins in Italian, scroll down to the English if you need to]