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Primary cilia control hedgehog signaling during muscle differentiation and are deregulated in rhabdomyosarcoma
W Fu, P Asp, B Canter, BD Dynlacht – Proceedings of the National Academy of …, 2014
Abstract The primary cilium acts as a cellular antenna, transducing diverse signaling pathways, and recent evidence suggests that primary cilia are important in development and cancer. However, a role for cilia in normal muscle development and rhabdomyosarcoma ( …

Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma
K Miyoshi, K Kohashi, F Fushimi, H Yamamoto… – Human Pathology, 2014
Abstract CXCR4 expression is reportedly correlated with both VEGF expression and poor prognosis in a variety of cancers. Its relation to CXCR7 is also noted in several malignancies, including rhabdomyosarcoma (RMS) cell lines. However, the correlations ..

A Rare Case of Testicular Embryonal Rhabdomyosarcoma Detected Incidentally on Bone Scan
GM Currie, C Skilton – Journal of Medical Imaging and Radiation Sciences, 2014
Abstract The role of nuclear medicine diagnostic bone scanning is well established, and the potential for detecting incidental findings is well-known. This case provides an insight into the specific role bone scanning plays in unraveling a complex clinical case. Furthermore, …

Rhabdomyosarcoma Arising in a Giant Congenital Melanocytic Nevus
MP Christman, JK Kerner, C Cheng, A Piris, AG Nepo… – Pediatric Dermatology, 2014
Abstract A number of lesions have been documented to arise within congenital melanocytic nevi (CMNs). Although the most frequent malignancy arising within a CMN is melanoma, the association between rhabdomyosarcoma and CMN has rarely been documented. We …

Cranial metastatic alveolar rhabdomyosarcoma mimicking hematological malignancy in an adolescent boy
T Patiroglu, B Isik, E Unal, O Canoz, K Deniz… – Child’s Nervous System, 2014
Background Widespread alveolar rhabdomyosarcoma (ARMS) with bone marrow involvement and with an unknown primary tumor, especially presenting with acute tumor lysis syndrome can be easily misdiagnosed as a hematological malignancy. Furthermore, …

Secondary malignant transformation of testicular teratomas: Case series and literature review.
L García-Labastida, GS Gómez-Macías… – Actas urologicas espanolas, 2014
… The predominante malignant somatic component were sarcomas; two cases of
chondrosarcoma, one rhabdomyosarcoma, and one case showing foci of chondrosarcoma
and rhabdomyosarcoma. The case of osteosarcoma is notable for its rarity. …

Parenteral nutrition in patients with inborn errors of metabolism – a therapeutic problem
L Kaluzny, M Szczepanik, Z Siwinska-Mrozek… – Eur Rev Med Pharmacol Sci, 2014
… Thus, limitations of intravenous lipid intake made it diffi- cult to maintain a good nutritional status.The third case was phenylketonuria associated with a facial region tumour (rhabdomyosarcoma), in which para-enteral nutrition was complicated because of a high …

Targeted polytherapy in small cell sarcoma and its association with doxorubicin
S Dumont, D Yang, AG Dumont, D Reynoso, JY Blay… – Molecular Oncology, 2014
… This work identifies a combination of targeted agents and doxorubicin that are effective against small cell sarcoma cell lines. Methods. Three small cell sarcoma cell lines were studied: RD18 (rhabdomyosarcoma), A204 (undifferentiated sarcoma) and TC 71 (Ewing’s sarcoma). …

Class I ADP-Ribosylation Factors Are Involved in Enterovirus 71 Replication
J Wang, J Du, Q Jin – PloS one, 2014
… GBF1 was also identified as a cellular factor crucial for EV71 replication in cells. Results. Expression of Class I Arfs is upregulated with EV71 infection. We previously showed that cellular COPI activity was required for EV71 replication in rhabdomyosarcoma (RD) cells [11]. …