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Diagnosis and treatment of lymph node metastases in pediatric rhabdomyosarcoma in the Netherlands: A retrospective analysis
CEJ Terwisscha van Scheltinga, P Spronk… - Journal of Pediatric Surgery, 2014
Background In pediatric rhabdomyosarcoma (RMS), evaluation of lymph node involvement
(N1) is an important staging aspect, but difficult to assess. The aim of our study was to
evaluate the assessment of lymph node infiltration and impact on outcome in N1 RMS ...

Rhabdomyosarcoma with Skin Metastasis: Report of a Case
S Ansari, S Yousefian, G Miri-Aliabad, T Ramim - Acta Medica Iranica, 2014
Abstract Rhabdomyosarcomas are the most common soft tissue sarcoma in adult and
children that accompany with skeletal muscle differentiation. Skin metastasis of
rhabdomyosarcomas is unusual and has only been sporadically reported in literature. In ...

Robotic-assisted surgery approach in a biliary rhabdomyosarcoma misdiagnosed as choledochal cyst
G Nakib, V Calcaterra, I Goruppi, P Romano… - Rare Tumors, 2014
Abstract Rhabdomyosarcoma is a soft tissue malignant tumor affecting 1% of children from 0
to 14 years. Preoperative imaging may not always be diagnostic for hepatobiliary
rhabdomyosarcoma and differential diagnosis with choledochal cyst (CC) could be difficult ...

Renal cell carcinoma with rhabdoid and sarcomatoid features presented as a metastatic thigh mass with an unusual immunohistochemical profile
AG Abdou, M Kandil, S Elshakhs, MS El-Dien… - Rare Tumors, 2014
... In this report, we describe a case of RCC metastasiz- ing to the thigh in a 70 year old male with
a highly pleomorphic morphology suggesting a high grade sarcoma that showed unequivocal
positivity for desmin directing the diagnosis for pleomorphic rhabdomyosarcoma. ...

CCN2 Enhances Resistance to Cisplatin-Mediating Cell Apoptosis in Human Osteosarcoma
HC Tsai, CY Huang, HL Su, CH Tang - PLOS ONE, 2014
... For example, in human rhabdomyosarcoma, CCN2 has been demonstrated to be a
useful therapeutic agent and disrupting CCN2 expression using CCN2-neutralizing
antibodies can enhance apoptosis and inhibit angiogenesis [33]. ...

Targeted therapy for sarcomas
C Forscher, M Mita, R Figlin - Biologics: Targets and Therapy, 2014
... gene in two cases (3.9%), both being leiomyosarcoma arising from the intraabdominal
cavity.81 Another study suggests that Akt Ser473 may be a key target residue for PTEN to
modulate the effects of IGF2 on acti- vating the PI3K/Akt pathway in rhabdomyosarcoma cells. ...