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Recent Papers on Rhabdomyosarcoma – 24 October 2014
From Google Scholar Alerts
Please note that some are abstracts requiring subscriptions or purchase of the full article, others provide a more comprehensive view of the paper.

Shorter-Duration Therapy Using Vincristine, Dactinomycin, and Lower-Dose Cyclophosphamide With or Without Radiotherapy for Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children’s Oncology Group
DO Walterhouse, AS Pappo, JL Meza, JC Breneman… – Journal of Clinical Oncology, 2014
Purpose Intergroup Rhabdomyosarcoma Study Group (IRSG) studies III and IV showed
improved failure-free survival (FFS) rates with vincristine, dactinomycin, and
cyclophosphamide (VAC; total cumulative cyclophosphamide dose, 26.4 g/m 2) compared …

Tumour volume reduction after neoadjuvant chemotherapy impacts outcome in localised embryonal rhabdomyosarcoma
TM Dantonello, M Stark, B Timmermann, J Fuchs… – Pediatric Blood & Cancer, 2014
Background Response (tumour volume reduction) to induction chemotherapy has been
used to stratify secondary local and systemic treatment of Intergroup Rhabdomyosarcoma
Study Group III (IRSG-III) embryonal rhabdomyosarcoma (RME) in consecutive CWS-trials …

An extremely rare case of testicular malign
neoplasm; alveolar subtype of rhabdomyosarcoma
with long term follow-up

T Ipekci, Y Akin, B Hoscan, A Tunckiran – Journal of Health Sciences, 2014
Abstract Testicular neoplasm usually occur in men aged between 15 and 35. These are
solid organ tumours and also should be operated when there is a suspicious clinical
findings. Testis tumours are levelled after histopathology evaluation. The medical, surgical …

MUSIC THERAPY AS A TOOL OF PSYCHOTHERAPY IN ADOLESCENCE CANCER PATIENTS
P Banerjee, S Mukhopadhyay, N Pal, A Mukhopadhyay – Annals of Oncology, 2014
… Among total patients 42% were ALL, 12% were NHL, 6% were Hodgkin disease, 12% were
Rhabdomyosarcoma, 8% were PNET, 8% were Germ cell Tumor, 4% were brain tumor, 4%
were Osteosarcoma and rest 4% were soft tissue and other patients. …

Brain Metastasis of Crystal-Deficient, CD68-Positive Alveolar Soft Part Sarcoma: Ultrastructural Features and Differential Diagnosis
MD Cykowski, J Hicks, DI Sandberg, A Olar, JA Bridge… – Ultrastructural Pathology, 2014
… metastasis. In the pediatric population, sarcomas metastatic to the CNS include
osteosarcoma, Ewing sarcoma/peripheral primitive neuroectodermal tumor,
rhabdomyosarcoma, clear cell sarcoma of soft tissue, and ASPS [15]. …

The mammalian Hippo pathway: regulation and function of YAP1 and TAZ
M Kodaka, Y Hata – Cellular and Molecular Life Sciences, 2014

… The Hippo pathway and RASSF6 are simultaneously activated and accomplish tumor suppressive roles in a parallel manner. In alveolar rhabdomyosarcoma (aRMS), PAX3-FOXO enhances RASSF4 expression, which leads to MST1 inhibition and YAP1 activation [105]. …

Analysis of Clinical Prognostic Factors for Adult Patients with Head and Neck Sarcomas
AE Chang, X Chai, SM Pollack, E Loggers, E Rodler… – Otolaryngology–Head and …, 2014
… org). Rhabdomyosarcoma (57%) had the lowest 2-year DSS rate. … tumors. In our
series of adult patients, the most common histological subtypes were angiosarcoma,
osteosarcoma, chondrosarcoma, and rhabdomyosarcoma. …

Pleomorphic Rhabdomyosarcoma Presenting as a Hypopharyngeal Mass
RA Crane, CM Johnson, GP Grice, DP Mullin, KK Bach – Head & Neck, 2014
Background: Rhabdomyosarcoma is a rare malignancy derived from skeletal muscle with
approximately 40% of cases involving the head and neck. The pleomorphic variant,
however, most commonly occurs in the extremities and has never, to our knowledge, been …

A mistaken identity: rhabdomyosarcoma of the middle ear cleft misdiagnosed as chronic suppurative otitis media with temporal lobe abscess
M Muranjan, S Karande, S Parikh, S Sankhe – BMJ Case Reports, 2014
Summary A 5-year-old girl presented with a 3-month history of left side facial palsy, followed sequentially by purulent ear discharge, complete external ophthalmoplaegia and blurred vision. On clinical examination she was febrile with left-sided conductive hearing loss. She …

Renal Liposarcoma in a Patient Undergoing Radiotherapy in Childhood: A Case Report
PN Aguiar Jr, B de Souza Gutierres, DP Guimaraes – Journal of Medical Cases, 2014
… the relevant literature. A 26-year-old male patient with a history of prostate
rhabdomyosarcoma that has been submitted to surgical resection and adjuvant
radiotherapy 23 years ago in the childhood was presented. He was asymptomatic …

Bone and Soft Tissue Pathology: Poster#021 ISOLATED CALCIFIED AMYLOIDOMA OF THE ABDOMINAL WALL MIMICKING SARCOMA.
P Dokouhaki, P Graham, R Kanthan – Pathology-Journal of the RCPA, 2014
Page 1. Copyright İ Royal College of pathologists of Australasia. Unauthorized reproduction of this article is prohibited. Rhabdomyosarcoma (RMS) is the most common soft tissue sar- coma among children. The identification …

LARYNGEAL PLEOMORPHIC RHABDOMYOSARCOMA
MU AKYOL, B SOZERI, T KUCUKALI…
Abstract: A case of an extremely unusual tumor of the larynx, pleomorphic
rhabdomyosarcoma, is presented with a review of literature. This is the fifth case of this
malignancy described in the larynx in the English language literature. A histopathological …

Parental Military Service, Agent Orange Exposure, and the Risk of Rhabdomyosarcoma in Offspring
S Grufferman, PJ Lupo, RI Vogel, HE Danysh… – Journal of Pediatrics
Objective To evaluate the role of parental military service-related exposures and
rhabdomyosarcoma (RMS) risk in offspring using data from a large case-control study of
childhood RMS. Study design Cases (n= 319) were enrolled from the third trial run by the …

Structural Analysis of the Human Fibroblast Growth Factor Receptor 4 Kinase.
E Lesca, A Lammens, R Huber, M Augustin – Journal of molecular biology, 2014
… variety of pathological disorders. FGFR4 is involved in myogenesis and muscle
regeneration. Mutations affecting the kinase domain of FGFR4 may cause cancer
eg breast cancer or rhabdomyosarcoma. Whereas FGFRs 1-3 …

Case in Point: Alveolar Rhabdomyosarcoma: A Rare Malignancy Presenting as Hypertension
N Verzosa, S Deese, H Kendhari
A biopsy sample of the mass was obtained, and pathology test results (Figure 3) were positive for myogenin, a specific marker for rhabdomyosarcoma (RMS). …