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Expression of the LIM homeobox domain transcription factor ISL1 (Islet-1) is frequent in rhabdomyosarcoma but very limited in other soft tissue sarcoma types
K ERLENBACH-WU, F Haller, H Taubert, P WU… - PAT, 2014
Summary The transcription factor ISL1 (islet-1) has emerged as a useful marker for
metastatic pancreatic well differentiated neuroendocrine neoplasms, but recent studies
showed wider expression in poorly differentiated neuroendocrine carcinomas from ...

Overexpression of GEFT, a Rho family guanine nucleotide exchange factor, predicts poor prognosis in patients with rhabdomyosarcoma
C Sun, C Liu, S Li, H Li, Y Wang, Y Xie, B Li, X Cui… - Int J Clin Exp Pathol, 2014
Abstract: Rhabdomyosarcoma (RMS) is one of the most common soft-tissue sarcomas in
children and adolescents with poor prognosis. Yet, there is lack of effective prognostic
biomarkers for RMS. The present study, therefore, aimed to explore potential biomarkers ...

Trabectedin: Novel Insights in the Treatment of Advanced Sarcoma
JP Lopez, C Gajdos, A Elias - Current Oncology Reports, 2014
... A phase 2 trial of trabectedin in children with recurrent rhabdomyosarcoma, Ewing sarcoma
and non-rhabdomyosarcoma soft tissue sarcomas: a report from the Children's Oncology Group.
Eur J Cancer. 2012;48(4):579–85. doi:10.1016/j.ejca.2011.09.027. ...

Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB)
K Bartelheim, D Sumerauer, U Behrends, D Kodetova… - Cancer Genetics, 2014
... demonstrated a tumor in the left thoracic cavity infiltrating the left atrium up to the posterior mitral
valve causing mitral insufficiency (Figure 1a). Ultrasound directed needle biopsy collected only
a few tumor cells and immunohistologic investigations suggested rhabdomyosarcoma ...

New Strategies in Ewing's Sarcoma: Lost in Translation?
FI Arnaldez, LJ Helman - Clinical Cancer Research, 2014
... 25. Baruchel S, Pappo A, Krailo M, Baker KS, Wu B, Villaluna D, et al. A phase 2 trial of trabectedin
in children with recurrent rhabdomyosarcoma, Ewing sarcoma and non-rhabdomyosarcoma
soft tissue sarcomas: a report from the Children's Oncology Group. ...

Life gained, years lost?
D Killock - Nature Reviews Clinical Oncology, 2014
... Basic research Rebooting rhabdomyosarcoma's operating system. Genetics SMARCA4 mutated
in SCCOHT. Advertisment. Science jobs. Faculty Positions Available in Beihang
University. Beihang University. Physician-Scientist, Dermatology. ...

Joint longitudinal and survival-cure models in tumour xenograft experiments
J Pan, Y Bao, H Dai, HB Fang - Statistics in Medicine, 2014
... cancer. A DNA analysis has formed the biochemical rationale for combining TMZ
and CPT-11. Our primary objective is to analyse the activity of TMZ combined with
CPT-11 against one rhabdomyosarcoma (Rh18) xenograft. Mice ...

Transmandibular surgical approach for malignant parapharyngeal space tumors
SG Patel - Operative Techniques in Otolaryngology-Head and …, 2014
... and cosmetic sequelae of treatment. More importantly, an unnecessary surgical
operation may be avoided completely with diagnosis of certain tumors such as
lymphoma or rhabdomyosarcoma. Open cervical biopsy and transoral ...

Development of a Cancer Treatment with the Concomitant Use of Low-Intensity Ultrasound: Entering the Age of Simultaneous Diagnosis and Treatment
M Emoto - Diagnostics, 2014
... Cancer Sci. 2011, 102, 1545–1552. 18. Emoto, M.; Iwasaki, H.; Oshima, K.; Kikuchi, M.;
Kaneko, Y.; Kawarabayashi, T. Characteristics of rhabdomyosarcoma cell lines derived from
uterine carcinosarcomas. Virchow Archiv. 1997, 431, 249–256. 19. ...

In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide
J Liu, Z Zhou, K Li, M Han, J Yang, S Wang - Archives of Virology
... cytopathic effect (CPE). A novel antisense oligonucleotide (EV5) was tested both
in rhabdomyosarcoma (RD) cells and in vivo using a mouse model, with a random
oligonucleotide (EV5R) of EV5 as a control. EV5 was identified ...

Small molecule compounds targeting the p53 pathway: are we finally making progress?
X Yu, S Narayanan, A Vazquez, DR Carpizo - Apoptosis
... irradiation. Mol Cell Biol 23:462–472; Canner JA, Sobo M, Ball S et al (2009) MI-63:
a novel small-molecule inhibitor targets MDM2 and induces apoptosis in embryonal
and alveolar rhabdomyosarcoma cells with wild-type p53. Br ...