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Expression of the LIM homeobox domain transcription factor ISL1 (Islet-1) is frequent in rhabdomyosarcoma but very limited in other soft tissue sarcoma types
K ERLENBACH-WU, F Haller, H Taubert, P WU… – PAT, 2014
Summary The transcription factor ISL1 (islet-1) has emerged as a useful marker for
metastatic pancreatic well differentiated neuroendocrine neoplasms, but recent studies
showed wider expression in poorly differentiated neuroendocrine carcinomas from …

Overexpression of GEFT, a Rho family guanine nucleotide exchange factor, predicts poor prognosis in patients with rhabdomyosarcoma
C Sun, C Liu, S Li, H Li, Y Wang, Y Xie, B Li, X Cui… – Int J Clin Exp Pathol, 2014
Abstract: Rhabdomyosarcoma (RMS) is one of the most common soft-tissue sarcomas in
children and adolescents with poor prognosis. Yet, there is lack of effective prognostic
biomarkers for RMS. The present study, therefore, aimed to explore potential biomarkers …

Trabectedin: Novel Insights in the Treatment of Advanced Sarcoma
JP Lopez, C Gajdos, A Elias – Current Oncology Reports, 2014
… A phase 2 trial of trabectedin in children with recurrent rhabdomyosarcoma, Ewing sarcoma
and non-rhabdomyosarcoma soft tissue sarcomas: a report from the Children’s Oncology Group.
Eur J Cancer. 2012;48(4):579–85. doi:10.1016/j.ejca.2011.09.027. …

Clinical and genetic features of rhabdoid tumors of the heart registered with the European Rhabdoid Registry (EU-RHAB)
K Bartelheim, D Sumerauer, U Behrends, D Kodetova… – Cancer Genetics, 2014
… demonstrated a tumor in the left thoracic cavity infiltrating the left atrium up to the posterior mitral
valve causing mitral insufficiency (Figure 1a). Ultrasound directed needle biopsy collected only
a few tumor cells and immunohistologic investigations suggested rhabdomyosarcoma …

New Strategies in Ewing’s Sarcoma: Lost in Translation?
FI Arnaldez, LJ Helman – Clinical Cancer Research, 2014
… 25. Baruchel S, Pappo A, Krailo M, Baker KS, Wu B, Villaluna D, et al. A phase 2 trial of trabectedin
in children with recurrent rhabdomyosarcoma, Ewing sarcoma and non-rhabdomyosarcoma
soft tissue sarcomas: a report from the Children’s Oncology Group. …

Life gained, years lost?
D Killock – Nature Reviews Clinical Oncology, 2014
… Basic research Rebooting rhabdomyosarcoma’s operating system. Genetics SMARCA4 mutated
in SCCOHT. Advertisment. Science jobs. Faculty Positions Available in Beihang
University. Beihang University. Physician-Scientist, Dermatology. …

Joint longitudinal and survival-cure models in tumour xenograft experiments
J Pan, Y Bao, H Dai, HB Fang – Statistics in Medicine, 2014
… cancer. A DNA analysis has formed the biochemical rationale for combining TMZ
and CPT-11. Our primary objective is to analyse the activity of TMZ combined with
CPT-11 against one rhabdomyosarcoma (Rh18) xenograft. Mice …

Transmandibular surgical approach for malignant parapharyngeal space tumors
SG Patel – Operative Techniques in Otolaryngology-Head and …, 2014
… and cosmetic sequelae of treatment. More importantly, an unnecessary surgical
operation may be avoided completely with diagnosis of certain tumors such as
lymphoma or rhabdomyosarcoma. Open cervical biopsy and transoral …

Development of a Cancer Treatment with the Concomitant Use of Low-Intensity Ultrasound: Entering the Age of Simultaneous Diagnosis and Treatment
M Emoto – Diagnostics, 2014
… Cancer Sci. 2011, 102, 1545–1552. 18. Emoto, M.; Iwasaki, H.; Oshima, K.; Kikuchi, M.;
Kaneko, Y.; Kawarabayashi, T. Characteristics of rhabdomyosarcoma cell lines derived from
uterine carcinosarcomas. Virchow Archiv. 1997, 431, 249–256. 19. …

In vitro and in vivo protection against enterovirus 71 by an antisense phosphorothioate oligonucleotide
J Liu, Z Zhou, K Li, M Han, J Yang, S Wang – Archives of Virology
… cytopathic effect (CPE). A novel antisense oligonucleotide (EV5) was tested both
in rhabdomyosarcoma (RD) cells and in vivo using a mouse model, with a random
oligonucleotide (EV5R) of EV5 as a control. EV5 was identified …

Small molecule compounds targeting the p53 pathway: are we finally making progress?
X Yu, S Narayanan, A Vazquez, DR Carpizo – Apoptosis
… irradiation. Mol Cell Biol 23:462–472; Canner JA, Sobo M, Ball S et al (2009) MI-63:
a novel small-molecule inhibitor targets MDM2 and induces apoptosis in embryonal
and alveolar rhabdomyosarcoma cells with wild-type p53. Br …